Decreased bone ultrasound velocity in premature infants conceived with assisted reproduction.
نویسندگان
چکیده
Quantitative ultrasound (QUS) measurement of tibial speed of sound (SOS) can be used to determine bone strength. Children conceived with assisted reproduction treatments (ART) are taller than naturally conceived (NC) children, so we hypothesized that these infants would have higher SOS levels than NC infants. Thirty-seven ART (ART group) and 51 NC neonates (NC group) were included in the study. Tibial initial SOS (iSOS) was measured within 96 hours of birth using QUS. Measurements were performed weekly until the infant was discharged from the hospital. The iSOS levels of the ART group (2823.41±110.8 m/sec) were lower than those of the NC group (2917.14±145.6 m/sec) (p=0.001). A decrease in SOS levels was observed in 39 of 53 infants who had serial scans. The difference in SOS levels between the first and last scan was significant (p<0.02). In vitro manipulation during the periconceptual period can result in metabolic alterations in bone mineral content. Contrary to our null hypothesis, bone SOS of infants in the ART group was found to be lower than in the NC group. Moreover, bone SOS decreases in early postnatal life. This result emphasizes the fact that even with advances in nutritional care, the ex utero environment remains a poor substitute for in utero development.
منابع مشابه
Quality of Life and General Health in Pregnant Women Conceived with Assisted Reproductive Technology: A Case-Control Study
Objective Infertility affects different aspects of life as well as quality of life (QOL) in infertile couples. Many infertile couples conceive via using Assisted Reproduction Technologies (ART). However, the effect of pregnancy and childbearing on QOL is not known in these couples. This study aim was to evaluate quality of life and general health during pregnancy and after successful treatment ...
متن کاملO-26: Comparison of Congenital Malformation of Infants Conceived by Assisted Reproductive Techniques versus Infants with Natural Conception in Tehran
Background: In many countries, 1% to 3% of newborn infants are conceived by Assisted Reproductive Techniques (ART). Despite the success of ART, there is concern about the risk of congenital malformations among these infants. We report our experience to determine whether use of ART is associated with an increase in major congenital malformations or adverse pregnancy outcomes Materials and Method...
متن کاملComparison of Congenital Abnormalities of Infants Conceived by Assisted Reproductive Techniques versus Infants with Natural Conception in Tehran
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O-28: Detection of Fetal Major Structural Abnormalities with US in ART Patients during One Year
Background: The aims were to determine the diagnostic accuracy of ultrasound sonography in detecting major structural anomalies on all patients who conceived during a year of infertility treatment [assisted reproductive technology (ART) or non-ART treatments] at the Royan Institute, and to study the outcome of cases with nuchal translucency (NT) ≥ 95th centile in the first trimester of pregnanc...
متن کاملPerinatal Outcomes of Newborn Infants Conceived by Assisted Reproductive Techniques in Royan Institute
Background The outcomes of such pregnancies have been rarely evaluated in our country. A descriptive study was planned to assess the health and condition of neonates conceived with assisted techniques in a one year period. MaterialsAndMethods At Royan Institute, Tehran, 443 women who became pregnant by one of the assisted techniques in vitro fertilization (IVF), intrauterine insemination (IUI) ...
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ورودعنوان ژورنال:
- The Turkish journal of pediatrics
دوره 57 1 شماره
صفحات -
تاریخ انتشار 2015